copper peptides
Copper Peptides in Winter: Protecting a Cold-Weather Skin Barrier
Can you keep using copper peptides in winter? Yes, and there's no reason to stop. What changes in winter isn't the peptide, it's everything around it. Cold, dry air and indoor heating pull water out of your skin, and GHK-Cu doesn't hold water in. So the winter job is to keep your copper peptide where it is and build a richer, gentler routine around it.
Below: what winter actually does to your skin barrier, what copper peptides can and can't do about it, a simple winter routine, and the mistakes that make winter skin worse.
What winter does to your skin barrier
Your skin barrier is the top layer of skin: flattened cells held together by fats, keeping water in and irritants out. In winter it gets squeezed from two sides. Cold air holds less moisture, and heating dries indoor air further still.
The American Academy of Dermatology puts it simply: with the drop in temperature and lack of humidity, skin can have a hard time holding on to moisture, which leads to itchy, dry skin and cracked lips. Turning up the heating makes dry heat that takes more moisture out of the air. Dry air can also make fine lines look more noticeable.
Once the barrier is short of water and its fats are disrupted, it gets touchier. Products you used all summer can start to sting, and skin takes longer to settle after anything irritating.
Cold air and dry air aren't the same thing
People lump these together, but it's mostly the dryness that hurts. A cold, damp coastal day can be kinder to skin than a warm, heated office. That's useful to know, because it means the fix isn't waiting for spring. It's putting moisture back: into the air where you can, and into your skin every day.
The AAD suggests a cool-mist humidifier in the bedroom rather than turning the heating up. You spend a third of your day there, and it's the one room you can control.

Using copper peptides in winter: what they do and don't do
What the research on GHK-Cu shows
GHK-Cu is a small copper peptide your body makes less of with age. A 2018 review in the International Journal of Molecular Sciences reports that it increases collagen, elastin and glycosaminoglycans, the molecules that help skin hold water, and describes a 12-week study in which 71 women with sun-aged skin used a GHK-Cu face cream and their skin measured denser and thicker, with shallower fine lines.
Here's how to read that for winter. What it did: it looked at skin structure and signs of ageing, mostly in cells plus one cream study. How it relates to our formulas: adjacent, not the same product or dose. What it doesn't prove: that copper peptides do anything specific for cold-weather dryness. Nobody has tested that. So copper peptides in winter are about keeping your long-term routine going, not a winter fix.
What copper peptides can't replace
GHK-Cu isn't a moisturiser. It doesn't pull water into skin the way glycerin does, and it doesn't seal water in the way petrolatum or shea butter does. A serum on its own, however good the peptide, won't stop winter dryness.
The AAD's tips for relieving dry skin are the part to take seriously: choose creams or ointments over lotions, put them on while skin is still damp, and look for ingredients such as jojoba oil, glycerin, hyaluronic acid, shea butter, petrolatum, lanolin or dimethicone. Those do the heavy lifting in January. The peptide rides along.
A winter routine with copper peptides
You don't need new actives for winter. You need richer textures and fewer ways to strip your skin.
Morning
- Cleanse lightly. If skin is tight or flaky, a rinse with lukewarm water is often enough in the morning.
- Serum on slightly damp skin. A few drops of the serum, pressed in.
- A richer moisturiser than you used in summer. The capsule cream has 0.5% GHK-Cu along with niacinamide, squalane and jojoba oil.
- Sunscreen. Broad-spectrum SPF 30 or higher on exposed skin. Winter sun is easy to forget, especially on bright days or around snow.
Evening
- Gentle cleanser, no hot water.
- Serum, then the capsule cream, a little more generously than in the morning.
- The balm stick on the rough bits. Cheekbones that catch the wind, the corners of the nose, knuckles, elbows.
If you're not sure which format to lean on, our guide to choosing between the serum, cream and stick matches each one to what your skin is doing. In winter, that usually means moving toward the richer end.

Hands, lips and the rest of you
Your face gets the attention, but hands usually show winter first. They get washed all day and meet the cold without cover. The AAD suggests gloves when your hands are in water, lip balm or petroleum jelly for dry lips, and moisturising several times a day.
The balm stick is useful here because it goes where a cream is messy. It's a water-free balm, 20 g, with 0.5% GHK-Cu, 15% jojoba oil and 10% squalane, that softens as it touches skin. Swipe it over knuckles and the backs of your hands after washing. For more on hands and the skin on them, see copper peptides for crepey skin and hands.
If you get cracked, bleeding or intensely itchy patches that don't settle with moisturising, see a dermatologist. Winter can bring out skin conditions that need proper treatment, not a thicker cream.
Common winter mistakes
- Long, hot showers. The AAD suggests five to ten minutes with warm, not hot, water, then patting skin dry.
- Keeping your summer exfoliation schedule. The AAD recommends cutting back on AHAs and BHAs in cold weather. Our guide to layering copper peptides with AHAs and BHAs covers how to scale back without stopping.
- Relying on a serum alone. Serums are thin by design. In winter, the cream on top matters more.
- Skipping sunscreen because it's cold. UV doesn't take the winter off.
- Fragranced products on dry skin. The AAD suggests avoiding fragrance and alcohol when skin is dry.

Frequently asked questions
Can you use copper peptides in cold weather?
Yes. GHK-Cu is generally well tolerated and doesn't rely on irritation to work, so there's no seasonal reason to stop. Just don't expect it to handle dryness on its own. Put a richer cream on top, use it on slightly damp skin, and keep sunscreen in the morning. If your skin is raw and stinging, pause everything but moisturiser until it settles.
Do you need a different moisturiser in winter?
Often, yes. Dermatologists suggest switching to heavier creams or ointments when it's cold, because they hold water in better than light lotions. You don't need to change your whole routine. Swapping the moisturiser, and using more of it at night, covers most of the difference.
Should you stop exfoliating in winter?
You don't have to stop, but cut back. The AAD recommends using fewer AHA and BHA products in cold weather, because they can irritate dry skin. Once or twice a week is plenty for most people. If your skin is flaking, that's dryness, not a reason to exfoliate more.
Does a humidifier help dry skin?
It helps with the cause rather than the symptom. Heating takes moisture out of indoor air, and dry air pulls water from skin. The AAD suggests a cool-mist humidifier in the bedroom. It's one of the few changes that works on your environment, not just on your face.
The short version
Keep your copper peptides in winter, but don't ask them to do a moisturiser's job. Winter dryness is mostly about humidity, so the biggest wins are a richer cream on damp skin, shorter warm showers, fewer exfoliating acids, a bedroom humidifier and sunscreen. Put the serum under the cream, use the balm stick on the rough patches, and see a dermatologist if cracked or itchy skin won't settle.
For the opposite climate, read our guide to skincare in extreme heat, and for a barrier that's already struggling, our complete skin barrier repair guide.
