body skincare

Copper Peptides and Keratosis Pilaris: What the Research Shows

 · 6 min read  · By Chantelle, Co-founder

Copper Peptides and Keratosis Pilaris: What the Research Shows

Do copper peptides help keratosis pilaris? We couldn't find a single study testing them on it, so we can't say they do. Keratosis pilaris, the small rough bumps on the upper arms and thighs, is caused by plugs of keratin in the hair follicles. GHK-Cu research is mostly cell work, animal wound studies and cosmetic studies on ageing facial skin, and none of it looked at those plugs.

Keratosis pilaris is harmless, but it's still a skin condition, and a pharmacist, GP or dermatologist is the right person to confirm it and suggest treatment. This article covers what it is, what actually has evidence behind it, what the copper peptide research does and doesn't show, and the everyday habits that help.

What keratosis pilaris is

The NHS describes keratosis pilaris as a very common, harmless condition where small bumps appear on the skin, usually on the arms, thighs or bottom. It happens when hair follicles get blocked with a build-up of keratin, the protein that also makes up hair and nails. It seems to run in families and isn't contagious.

The bumps are often skin-coloured. The NHS notes they can look red on white skin and darker on brown or black skin. Skin may feel rough or itchy, and it's often worse in winter.

Does it go away?

Slowly, for many people. The NHS says most people have it for years and it may clear up by itself. The American Academy of Dermatology adds that many people find the bumps clear in summer and come back in winter, and that people in dry climates or who swim a lot may have them all year.

Smiling woman with natural skin texture and light freckles
Keratosis pilaris is common, harmless and often seasonal.

What has evidence for keratosis pilaris

You don't have to treat it. The AAD says treatment can help if the itch, dryness or look of the bumps bothers you, but that it can't cure keratosis pilaris, so it's about keeping the bumps under control.

Its treatment guide lists two groups of ingredients:

  • Moisturisers containing urea or lactic acid, applied after every bath or shower while skin is still damp, two or three times a day.
  • Exfoliating treatments containing alpha hydroxy acids such as glycolic or lactic acid, salicylic acid, urea, or a retinoid, used as often as your dermatologist recommends.

The AAD says clearing takes time, and if you don't see improvement after 4 to 6 weeks on a treatment plan, tell your dermatologist. Laser treatment and steroid creams are further options, though the NHS notes they aren't usually available on the NHS.

What the research on copper peptides and keratosis pilaris shows

None exists that we could find. A 2015 review in BioMed Research International summarises most of the GHK-Cu work: cell studies on collagen and related molecules, wound studies in animals, and cosmetic studies on ageing skin looking at firmness, fine lines and sun damage.

Here's our rule of three. What the research did: looked mostly at collagen, wound healing and signs of ageing, not at keratin plugs in hair follicles. How it relates to keratosis pilaris: it doesn't, directly. GHK-Cu isn't an exfoliant and doesn't loosen keratin. What it doesn't prove: that GHK-Cu, or any product containing it, makes the bumps smoother or less visible.

Abstract glass molecular sculpture representing a copper peptide
GHK-Cu research looks at collagen deep in the skin. Keratosis pilaris starts at the surface.

Why we don't make keratosis pilaris claims

There are ingredients with evidence for keratosis pilaris, and copper peptides aren't among them. So we don't describe any of our products as helping it. If your bumps are sore, inflamed or spreading, or you're not sure it's keratosis pilaris at all, get it checked. The NHS suggests speaking to a pharmacist if looking after your skin at home isn't helping or the skin becomes inflamed.

Everyday habits that help

The NHS list of things to do at home is short and practical:

Do Don't
Moisturise regularly Use perfumed products that dry the skin
Use mild, unperfumed soap Use harsh scrubs, which can make it worse
Exfoliate gently with a washcloth Take hot baths or showers
Take cool or lukewarm showers Scratch, pick or rub the bumps

Go easy on stacking exfoliants. A strong acid, a scrub and a retinoid at once is more likely to irritate skin than smooth it. Our guide to layering copper peptides with AHAs and BHAs explains why acids and copper peptides belong in separate steps.

Using copper peptides on your body in general

Plenty of people use copper peptides beyond the face for general skin ageing, such as crepey texture on the hands or neck. That's a different goal from keratosis pilaris, and it's covered in our guides to copper peptides for crepey skin and hands and the neck and décolletage.

koppā GHK-Cu capsule cream in its tube
The capsule cream: 0.5% GHK-Cu in small blue beads that open as you rub it in.

If you use a copper peptide moisturiser, such as our capsule cream, patch test first. Keep it separate from your acid or urea step, and if a dermatologist has given you a treatment for keratosis pilaris, keep following that. Our guide to the serum, cream and stick compares the three formats.

Frequently asked questions

Can copper peptides get rid of keratosis pilaris?

There's no evidence that they can. We couldn't find a study of GHK-Cu on keratosis pilaris, and it isn't an exfoliant. The AAD lists moisturisers with urea or lactic acid and exfoliating treatments as the main options, and says treatment controls the bumps rather than curing them. A pharmacist, GP or dermatologist can help you choose.

Is keratosis pilaris the same as body acne?

No. Keratosis pilaris is a build-up of keratin blocking hair follicles, and the NHS describes it as harmless and not contagious. Acne involves follicles blocked with oil and dead skin cells, and it can form painful spots. They can look alike at a glance, which is one reason it's worth getting a proper diagnosis. Our article on GHK-Cu and oily, acne-prone skin covers breakouts.

Why is keratosis pilaris worse in winter?

Dry air seems to be the main reason. The NHS notes it often gets worse in winter, and the AAD says many people see bumps clear in summer and return in winter, while people in dry climates may have them all year. That's why regular moisturising, straight after a lukewarm shower, is the first habit dermatologists suggest.

The short version

Keratosis pilaris is a common, harmless build-up of keratin in the hair follicles. Moisturisers with urea or lactic acid and gentle exfoliating treatments are what the AAD recommends, and treatment controls it rather than curing it. We couldn't find any study of copper peptides for keratosis pilaris, so we don't claim they help. Moisturise often, skip harsh scrubs and hot showers, and ask a pharmacist, GP or dermatologist if it bothers you.

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